Pre-Conference Workshop

Pre-Conference Workshop

COMMON FEATURES OF NEURODEGENERATIVE DISEASES:
EXPLORING THE BRAIN-EYE CONNECTION AND BEYOND

Pre-Conference Full Day Satellite Workshop
Tuesday, March 26, 2019
08:30 -17:00

Pre-Registration is required. To register, please click here

 Co-Chair: Guojun Bu (USA)

 
 Co-Chair: Adriana Di Polo (Canada)
​Co-Chair: Todd Golde (USA) 

 
INTRODUCTORY REMARKS 
08:30WELCOME AND INTRODUCTIONS
Diane Bovenkamp (USA)
 
08:40

DEFINITIONS AND GENERAL DISCUSSION PRIMER
Guojun Bu (USA)

Adriana Di Polo (Canada)

Todd Golde (USA)

 
 DEFINITIONS AND GENERAL DISCUSSION PRIMER. SESSION I – WHY HAVE NEUROPROTECTIVE STRATEGIES FAILED AND HOW CAN WE MAKE IMPROVEMENTS? 
 SESSION I DISCUSSION PRIMER
Chair: Todd Golde (USA)
 
 Chair: Adriana Di Polo (Canada)  
09:05COMPLEXITIES IN GENETICS AND SYSTEMS BIOLOGY OF ALZHEIMER'S DISEASE AND RELATED DEMENTIAS
Nilufer Ertekin-Taner (USA)
 
09:25THE ACADEMIC-INDUSTRIAL COMPLEXITY: FAILURE TO LAUNCH TRANSLATIONAL THERAPIES FOR OCULAR DISEASES
Speaker: To be confirmed
 
09:45NERVE GROWTH FACTOR GENE THERAPY CLINICAL TRIAL FOR ALZHEIMER'S DISEASE: IN PROGRESS
Speaker: Mark Tuzsynski, USA
 
10:05

CLINICAL DEVELOPMENT OF A GENE THERAPY FOR AN INHERITED RETINAL DEGENERATIVE DISEASE: A SUCCESS STORY
Speaker: To be confirmed

 
10:25RE-PURPOSING DIABETES DRUGS FOR ALZHEIMER'S DISEASE: RATIONALE AND EXPERIENCE
Steven Arnold (USA)
 
10:45SECTION I GENERAL DISCUSSION / Q and A 
11:05COFFEE BREAK 
 

SESSION II - CAN WE MAKE MODELS THAT BETTER RECAPITULATE THE REAL-WORLD DISEASE SITUATION AND, IF SO, HOW WOULD WE KNOW THAT WE'VE SUCCEEDED?

 

 

 
11:25SESSION II DISCUSSION PRIMER 
 

 

Chair: Todd Golde (USA)

 
 Chair: Guojun Bu (USA)  
11:30CHIMERIC ALZHEIMER'S DISEASE MODEL: STEM-CELL-DERIVED HUMAN NEURONS TRANSPLANTED INTO MOUSE BRAIN
Bart De Strooper (United Kingdom)
 
11:50MODELING NEURODEGENERATIVE DISEASES WITH HUMAN NEURONS GENERATED BY DIRECT NEURONAL REPROGRAMMING
Andrew Yoo (USA)
 
12:10ADVANCES IN THE USE OF HUMAN PLURIPOTENT STEM CELLS, ORGANOIDS, AND TRANSPLANTABLE PHOTORECEPTORS AS MODELS FOR RETINAL DEGENERATION
Speaker: To be confirmed
 
12:30TOWARDS A MORE COMPLETE REPRESENTATION OF HUMAN DISEASE: ALZHEIMER'S MOUSE MODEL TAKES INTO ACCOUNT BETA-AMYLOID, TAU, AND SEEDING
Virginia Lee (USA)
 
12:50RETINA-IN-A-DISH: COMPLEX HUMAN IPSC-DERIVED 3D RETINAL ORGANOIDS
M. Valeria Canto-Soler (USA)
 
13:10SECTION II DISCUSSION / Q and A 
13:30LUNCH BREAK 
 SESSION III - HOW DO WE IMPROVE OUR UNDERSTANDING OF THE IMPACT OF CO-MORBIDITIES AND SYNERGISTIC PROCESSES, AND HOW DO WE EFFECTIVELY STUDY THEM? 
14:45SESSION III DISCUSSION PRIMER 
 Chair: Adriana Di Polo (Canada)  
 

Chair: Guojun Bu (USA)

 

 
14:50
GENETICS AND GENOMICS APPROACHES TO STUDY RESILIENCE TO COGNITIVE AGING AND ALZHEIMER’S DISEASE 
Cathrine Kaczorowski (USA)
 
15:10MULTIMODAL PREVENTIVE TRIALS FOR ALZHEIMER'S DISEASE: WHAT CAN WE LEARN FROM THE FINGER STUDY
Speaker: Miia Kivipelto, Sweden
 
15:30CONTRIBUTIONS TO ALZHEIMER'S DISEASE AND RELATED DEMENTIAS, STROKE, AND CEREBRAL HEMORRHAGES
Speaker: Brian Bacskai, USA
 
15:50SLEEP AND ALZHEIMER'S DISEASE: A BI-DIRECTIONAL RELATIONSHIP
David Holtzman (USA)
 
16:10DEMENTIA IN THE OLDEST OLD
Claudia Kawas (USA)
 
16:30SECTION III DISCUSSION / Q and A 
16:50CLOSING REMARKS/DISCUSSION